发明名称 |
METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS |
摘要 |
The present invention provides, inter alia, methods for detecting whether a subject has an infection. These methods include (a) incubating a test sample from a subject suspected of having an infection with a labeled molecule, such as a labeled nucleoside analog, that is preferentially incorporated into a pathogenic microorganism for a period of time sufficient for the pathogenic microorganism to incorporate the labeled molecule; (b) removing any unincorporated labeled molecule from the test sample; and (c) detecting the labeled molecule within the pathogenic microorganism, if any, in the test sample, wherein the presence of labeled molecule within the pathogenic microorganism indicates that the subject has an infection. |
申请公布号 |
US2014228248(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
US201214347463 |
申请日期 |
2012.09.24 |
申请人 |
BIOMED VALLEY DISCOVERIES, INC. |
发明人 |
Saha Saurabh;Bettegowda Chetan;Tung David |
分类号 |
C12Q1/18;C12Q1/16;C12Q1/48;C12Q1/04 |
主分类号 |
C12Q1/18 |
代理机构 |
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代理人 |
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主权项 |
1. A method for detecting whether a subject has an infection comprising:
(a) incubating a test sample from a subject suspected of having an infection with a labeled molecule that is preferentially incorporated into a pathogenic microorganism for a period of time sufficient for the pathogenic microorganism to incorporate the labeled molecule; (b) removing any unincorporated labeled molecule from the test sample; and (c) detecting the labeled molecule within the pathogenic microorganism, if any, in the test sample, wherein the presence of labeled molecule within the pathogenic microorganism indicates that the subject has an infection. |
地址 |
Kansas City MO US |