发明名称 |
ARYL SUBSTITUTED INDOLES AND THEIR USE AS BLOCKERS OF SODIUM CHANNELS |
摘要 |
The invention relates to aryl and heteroaryl substituted compounds of Formula (I), and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein G, R1, and Z1-Z5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain. |
申请公布号 |
EP2582666(B1) |
申请公布日期 |
2014.08.13 |
申请号 |
EP20110795252 |
申请日期 |
2011.06.16 |
申请人 |
PURDUE PHARMA L.P. |
发明人 |
KYLE, DONALD, J.;NI, CHIYOU;TAFESSE, LAYKEA;YAO, JIANGCHAO |
分类号 |
C07D209/12;A61K31/404;A61K31/416;A61P25/00;C07D209/16;C07D231/56;C07D471/04 |
主分类号 |
C07D209/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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