发明名称 Benzylbenzene derivatives and methods of use
摘要 Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
申请公布号 US8802637(B2) 申请公布日期 2014.08.12
申请号 US201314042408 申请日期 2013.09.30
申请人 Theracos, Inc. 发明人 Chen Yuanwei;Cheng Huawei;Li Shengbin;Wu Yuelin;Feng Yan;Lv Binhua;Xu Binhua;Seed Brian;Hadd Michael J.;Song Yanli;Du Jiyan;Wang Congna;Roberge Jacques Y.
分类号 C07H7/04 主分类号 C07H7/04
代理机构 Kilpatrick Townsend & Stockton LLP 代理人 Kilpatrick Townsend & Stockton LLP ;Kezer William B.
主权项 1. A compound of Formula IA:wherein V is oxygen; W is C1-C6 alkylene; X is oxygen; Y is a member selected from the group consisting of C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C10 cycloalkyl and (C1-C4 alkyloxy)C1-C3 alkyl; and R1 is chloro.
地址 Marlborough MA US