发明名称 MALONAMIDAS COMO ANTAGONISTAS DE OREXINAS.
摘要 The present invention relates to compounds of formula I wherein Ar1, Ar2, R, R1, R2, R3 and n are as defined herein or to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. Compounds of formula I are orexin receptor antagonists and may be useful in the treatment of disorders, in which orexin pathways are involved like sleep disorders.
申请公布号 BRPI0808737(A2) 申请公布日期 2014.08.12
申请号 BR2008PI08737 申请日期 2008.03.05
申请人 F. HOFFMANN-LA ROCHE AG 发明人 LUCA GOBBI;HENNER KNUST;PARICHER MALHERBE;MATTHIAS NETTEKOVEN;EMMANUEL PINARD;OLIVIER ROCHE;MARK ROGERS-EVANS
分类号 C07C233/08;A61K31/167;C07C233/15;C07C233/22 主分类号 C07C233/08
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