Melatonin and immunostimulating substance-based compositions

摘要

The present invention relates to synergistic associations of melatonin and other active substances and cosmetic compositions suitable for treating all those manifestations causing or accompanying the aging of skin, hair and other tissues. In particular, the invention is based on the use of melatonin associated with immunoactive and antioxidant substances significantly potentiating its antiaging activity, remarkably reducing free radical formation and thereby improving the aspect of both skin and hair.

主权项

1. A cosmetic composition for treatment of natural aging and photoaging of tissues and cutaneous annexes, the composition comprising: an excipient, pharmaceutically acceptable adjuvants and additives, and an effective amount of a mixture of substances comprising: (i) melatonin; (ii) at least one immunostimulant selected from the group consisting of ectoine, beta-glucan, and carboxymethyl betaglucan; and (iii) at least one antioxidant; wherein at least one of the substances of the mixture is adsorbed or bound to chitin nanofibrils; provided that the composition does not comprise tocotrienols.