| 主权项 |
1. A method of treating muscular dystrophies comprising administering to a subject a nitric oxide releasing compound of formula (Ia)
M-X—Y—ONO2 (Ia) or enantiomers or diastereoisomers thereof, wherein in the general formula (Ia), M, X and Y have the following meanings: M is a residue X is —O—, —S— or —NR1—, wherein R1 is H or linear or branched C1-C6 alkyl; Y is a bivalent radical having the following meanings:
straight or branched C1-C20 alkylene being optionally substituted with one or more of the substituents selected from the group consisting of: halogen atoms, hydroxy, —ONO2 and T, wherein T is —OC(O)(C1-C10 alkyl)-ONO2 or —O(C1-C10 alkyl)-ONO2; or—C5-C7 cycloalkylene group optionally substituted with linear or branched C1-C10 alkyl group. |
