| 摘要 |
PURPOSE: An apparatus for detecting post-translational modification is provided to accurately detect protein modification and to search various peptide-based protein modifications. CONSTITUTION: An apparatus(100) for detecting protein modification comprises: a fragment ion mass pattern generation unit(400), protein modification database(300), and a mass shift detection unit. The fragment ion mass pattern generation unit cleaves a peptide-based protein modification sequence with a virtual enzyme and generates virtual fragment ions. The protein modification database stores protein modification information including the kind and mass of protein modification. The mass shift detection unit detects one or more protein modification. [Reference numerals] (200) Protein modification sequence database; (300) Protein modification database; (400) Fragment ion mass pattern generation unit; (500) Protein modification searching unit; (AA) Mass analysis information and peptide sequence information of analysis target protein; (BB) Protein modification kind and location information |
