发明名称 Method of Diagnosis or Prognosis of a Neoplasm Comprising Determining the Level of Expression of a Protein in Stromal Cells Adjacent to the Neoplasm
摘要 The invention provides diagnostic and therapeutic methods for neoplastic disease patients with neoplasms of, for example, the breast, skin, kidney, lung, pancreas, rectum and colon, prostate, bladder, epithelial, non-epithelial, lymphomas, sarcomas, melanomas, and the like, wherein the method comprises determining the level of expression o caveolin-1, caveolin-2, vimentin, calponin2, tropomyosin, gelsolin, prolyl 4-hydroxylase alpha, EF-I-delta, or M2-isoform of pyruvate kinase in stromal cells adjacent to the neoplasm.
申请公布号 US2014221496(A1) 申请公布日期 2014.08.07
申请号 US201314090538 申请日期 2013.11.26
申请人 Thomas Jefferson University 发明人 Lisanti Michael P.;Sotgia Federica;Pestell Richard G.
分类号 A61K31/138 主分类号 A61K31/138
代理机构 代理人
主权项
地址 Philadelphia PA US
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