| 发明名称 |
Templated Islet Cells and Small Islet Cell Clusters for Diabetes Treatment |
| 摘要 |
A population of small reaggregated islets or clusters engineered from individual islet cells and having improved characteristics as compared to native isolated islets. |
| 申请公布号 |
US2014219997(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
US201414249016 |
申请日期 |
2014.04.09 |
| 申请人 |
The University of Kansas |
发明人 |
Berkland Cory;Stehno-Bittel Lisa A.;Siahaan Teruna;Ramachandran Karthik |
| 分类号 |
C12N5/071;A61K45/06;A61K35/39 |
主分类号 |
C12N5/071 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A population of reaggregated islets, wherein at least 80% of said reaggregated islets have a diameter of less than 90 μm, the reaggregated islets have low diffusion barriers relative to native large islets, and wherein the reaggregated islets have high cell viability relative to native small and large islets, and wherein reaggregated islet insulin production is characterized by levels that are greater than native isolated islets. |
| 地址 |
Lawrence KS US |
