| 发明名称 |
Novel crystals and process of making 5-(-methyl)-2-methoxy-benzoic acid |
| 摘要 |
The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. |
| 申请公布号 |
US2014221444(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
US201414171366 |
申请日期 |
2014.02.03 |
| 申请人 |
FURIEX PHARMACEUTICALS, INC. |
发明人 |
Anzalone Luigi;Villani Frank J.;Teleha Chrisptoher A.;Feibush Penina;Fegely Barry |
| 分类号 |
C07D233/64 |
主分类号 |
C07D233/64 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of treating a mammal suffering from irritable bowel syndrome, pain or another opioid receptor disorder comprising administering to said mammal an effective amount of a Form β crystal of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid. |
| 地址 |
MORRISVILLE NC US |
