| 发明名称 |
METABOLOMIC MARKERS FOR PRETERM BIRTH |
| 摘要 |
Panels, kits, and methods for diagnosing or predicting the likelihood of occurrence of preterm birth (PTB) in a subject are disclosed. An exemplary panel includes at least one of a first marker from a first group of markers and a second marker from a second group of markers. A significant decrease in the first marker and a significant increase in the second marker measured in a sample taken from a subject during the second trimester of pregnancy are diagnostic or predictive of an increased risk of preterm birth for the subject. |
| 申请公布号 |
US2014221236(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
US201414171550 |
申请日期 |
2014.02.03 |
| 申请人 |
Borowski Kristi S.;Murray Jeff;Ryckman Kelli K. |
发明人 |
Borowski Kristi S.;Murray Jeff;Ryckman Kelli K. |
| 分类号 |
G01N33/68;G01N33/92;G01N33/49 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A panel for diagnosing or predicting the likelihood of occurrence of preterm birth (PTB) in a subject, the panel comprising at least one of:
(a) a first marker from a first group of markers that when significantly lower in concentration compared to a term birth control is predictive of preterm birth; and (b) a second marker from a second group of markers that when significantly higher in concentration compared to the term birth control is predictive of preterm birth, wherein a significant decrease in the first marker and a significant increase in the second marker measured in serum taken from a subject during the second trimester of pregnancy compared to a control is diagnostic or predictive of an increased risk of preterm birth for the subject. |
| 地址 |
Byron MN US |
