| 主权项 |
1. A mixing system, comprising:
a reaction well including a vessel having an upper opening, a barrier, and a bottom, wherein the vessel is configured to contain at least one reagent and at least one solution, the barrier being configured to seal the upper opening to create a closed vessel; a magnetically responsive bead having an optical coating thereon, the optical coating being configured to reduce any optical interference with optic measurement systems, and a clear parylene coating encapsulating the bead and the optical coating; a heat source positioned near the reaction well and being operable to heat solution and reagents contained within the closed vessel; a first magnet positioned near a first side of the reaction well and being configured to provide a first magnetic field through the reaction well, the first magnetic field being of sufficient strength so as to be capable of moving the magnetically responsive bead within the reaction well; a system for oscillating the strength of the first magnetic field to alter a position of the magnetically responsive bead within the reaction well; a second magnet positioned near a second side of the reaction well and configured to provide a second magnetic field through the reaction well, the second magnetic field being of sufficient strength so as to be capable of moving the magnetically responsive bead within the reaction well; a system for oscillating the strength of the second magnetic field to alter a position of the magnetically responsive bead within the reaction well; and wherein the oscillating systems for the first magnetic field and the second magnetic field operate out of phase with one another such that the magnetically responsive bead oscillates between an upper position within the closed vessel and a bottom position within the closed vessel such that the solution and reagents are mixed while being heated. |
