| 发明名称 |
NOVEL INHIBITORS OF THE ENZYME ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE (ICMT) |
| 摘要 |
<p>The invention relates to novel inhibitors of the enzyme isoprenylcysteine carboxyl methyltransferase, to the synthesis methods thereof, and to the use thereof as antitumour agents. Said inhibitors are derived from aliphatic amines and are used in the prevention and/or treatment of pathologies caused by the enzyme ICMT.</p> |
| 申请公布号 |
WO2014118418(A1) |
申请公布日期 |
2014.08.07 |
| 申请号 |
WO2014ES70071 |
申请日期 |
2014.02.03 |
| 申请人 |
UNIVERSIDAD COMPLUTENSE DE MADRID |
发明人 |
LÓPEZ RODRÍGUEZ, MARÍA LUZ;ORTEGA GUTIÉRREZ, SÍLVIA;MARTÍN-FONTECHA CORRALES, MARÍA DEL MAR;BALABASQUER PEÑA, MOISÉS;ORTEGA NOGALES, FRANCISCO JESÚS;MARÍN RAMOS, NAGORE ISABEL |
| 分类号 |
C07C237/22;A61K31/16;A61P35/00;C07C311/32 |
主分类号 |
C07C237/22 |
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