发明名称 Surface modification
摘要 The invention relates to a carrier comprising at least one substrate, which has a coating in at least certain regions produced from individual modules by plasma polymerization, and the coating has one or more free spaces in at least certain regions for accommodating at least one solution containing a biological sample.
申请公布号 US8795787(B2) 申请公布日期 2014.08.05
申请号 US200812734079 申请日期 2008.10.10
申请人 Greiner Bio-One GmbH 发明人 Jehle Heinrich
分类号 C08J7/00;C08J7/16;C08J7/18;H05H1/24;B05D5/00;B05D1/00;C40B20/02;C40B30/04;C40B40/06;C40B60/12;B08B17/00;B01L3/00 主分类号 C08J7/00
代理机构 Collard & Roe, P.C. 代理人 Collard & Roe, P.C.
主权项 1. Method of modifying at least certain regions of a surface of a carrier, whereby a coating of at least one substrate containing individual modules of at least one monomer species is deposited via plasma polymerization, and free spaces are created in at least certain regions for accommodating at least one solution by activating the surface of the substrate in the plasma before plasma polymerization, wherein activation takes place in a reactor using a reaction mixture containing a carrier gas and a reaction gas, wherein the carrier gas is an inert gas and the reaction gas is selected from the group consisting of oxygen, ammonia, H2, N2, CO2, and C2H2, and wherein activation is conducted at a 9 to 18 times higher power input than plasma polymerization, and generates binding sites, the carrier immobilizing nucleic acids whilst simultaneously repelling proteins.
地址 Frickenhausen DE