发明名称 |
TAMPER-RESISTANT ORAL PHARMACEUTICAL DOSAGE FORM COMPRISING A PHARMACOLOGICALLY ACTIVE INGREDIENT, AN OPIOID ANTAGONIST AND/OR AVERSIVE AGENT, POLYALKYLENE OXIDE AND ANIONIC POLYMER |
摘要 |
The invention relates to a pharmaceutical dosage form for oral administration having a breaking strength of at least 300 N and comprising (i) a pharmacologically active ingredient; (ii) an opioid antagonist and/or an aversive agent; (iii) a polyalkylene oxide having an average molecular weight of at least 200,000 g/mol; and (a) further comprising (iv) an anionic polymer; and/or (b) having a storage stability at 40° C. of at least 3 months. |
申请公布号 |
KR20140096062(A) |
申请公布日期 |
2014.08.04 |
申请号 |
KR20147013076 |
申请日期 |
2012.11.15 |
申请人 |
GRUNENTHAL GMBH |
发明人 |
GEISSLER ANJA;BARNSCHEID LUTZ;SCHWIER SEBASTIAN;BARTHOLOMAEUS JOHANNES |
分类号 |
A61K9/20;A61K31/485;A61K47/12 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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