COMPOSITIONS AND METHODS FOR REGULATING THERMOGENESIS AND MUSCLE INFLAMMATION USING METRNL AND METRN
摘要
<p>The invention provides compositions and methods for regulating thermogenesis and muscle inflammation through modulation of Metrnl and/or Metrn activity and/or expression. Also provided are methods for preventing or treating metabolic disorders and muscle inflammation disorders in a subject through modulation of Metrnl and/or Metrn activity and/or expression. Further provided are methods for identifying compounds that are capable of treating metabolic disorders and muscle inflammation disorders by modulating Metrnl and/or Metrn activity and/or expression.</p>
申请公布号
WO2014116556(A2)
申请公布日期
2014.07.31
申请号
WO2014US12243
申请日期
2014.01.21
申请人
DANA-FARBER CANCER INSTITUTE, INC.
发明人
SPIEGELMAN, BRUCE, M.;RAO, RAJESH, R.;LONG, JONATHAN, Z.