发明名称 MODIFIED CREATINE COMPOUNDS
摘要 The invention discloses creatine derivatives that are represented by Formula (I), Formula (II), and Formula (III); wherein Z is a functional group; Y is a mitochondrial targeting agent, a cationic ammonium group, or a polypeptide containing at least one positively charged amino acid residue; each R1 is independently hydrogen, alkyl, or a phosphate group; R2 a linker; R3 is a spacer group; R4 is hydrogen, alkyl, aryl, or heterocyclic; or R4 and R1, or R4 and R3, together with the nitrogen atoms to which they are attached form a heterocyclic ring, and W is hydrogen or alkyl.
申请公布号 EP2758411(A2) 申请公布日期 2014.07.30
申请号 EP20120769555 申请日期 2012.09.18
申请人 GENCIA CORPORATION 发明人 KHAN, SHAHARYAR, M.;GADWOOD, ROBERT, C.;ROMERO, ARTHUR, GLENN
分类号 C07F9/54;A61K31/66;A61P21/00 主分类号 C07F9/54
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