摘要 |
<p>The invention relates to organic chemistry. Its use in isoprenoid chemistry allow to achieve the technical result in the form of a universal, workable and economical method for producing polyprenyl phosphates. This result is achieved in that in the method for producing polyprenyl phosphates of general structural formula (I) ,
where each isoprene unit contains 5 carbon atoms, W means a É-end isoprene unit, T means a trans-isoprene unit, C means a cis-isoprene unit, S means a 2,3-dihydroisoprene unit, a = 0-10, b = 0-39, c = 0-1, a + b + c = 4-40, and X means a group of the formula OPO 3 MM', wherein M and M' are identical or different and are a hydrogen cation or monovalent inorganic or organic cation, or M and M' together are divalent inorganic or organic cation, the phosphorylation of the relevant polyprenol or a mixture of oligomer homologues, where X means hydroxyl group, using a substituted ammonium salt of phosphoric acid in the presence of condensing agent, is carried out in a medium consisting of first aprotic organic solvent; and a polyprenyl phosphate in the form of mono- or disubstituted salts thereof with monovalent cations or in the form of salts thereof with divalent cations is isolated by extraction and precipitation.</p> |