发明名称 Nasal preparation, used to topical, protective, nurturing/supporting application to treat irritation/swelling in nasal mucosa due to e.g. allergies, includes mineral salt, water, alcohols, poloxamer surfactants, and additives e.g. enzyme
摘要 <p>Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives comprising essential oils, water-soluble vitamins, enzymes, proteins and zinc salts, other H-regulators, preserving agents, and/or consistency agents, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. An independent claim is included for spay- or spray applicator comprising 10-100 ml of the preparation.</p>
申请公布号 DE102013001151(A1) 申请公布日期 2014.07.24
申请号 DE20131001151 申请日期 2013.01.24
申请人 MERZ PHARMA GMBH & CO. KGAA 发明人 BERLEKAMP, UWE;MÖHLE, MELANIE
分类号 A61K33/14;A61K31/047;A61K31/765;A61K33/30;A61K36/00;A61K38/43;A61P11/02;A61P37/08 主分类号 A61K33/14
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