发明名称 |
Nasal preparation, used to topical, protective, nurturing/supporting application to treat irritation/swelling in nasal mucosa due to e.g. allergies, includes mineral salt, water, alcohols, poloxamer surfactants, and additives e.g. enzyme |
摘要 |
<p>Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. Nasal preparation comprises: 0.5-4 wt.% of mineral salt having at least 70 wt.%, based on the salt mixture, of sodium chloride salt as a main active ingredient comprising table salt, rock salt and sea salt different origin; 56.5-84.5 wt.% of water; 6-20 wt.% of one or more alcohols comprising ethylene glycol, propylene glycol and/or glycerol; 6-20 wt.% of one or more poloxamer surfactants (polyoxyethylene-polyoxypropylene block polymers) with an average molar mass of 1800-18000 g/mole; and 0-5 wt.% of additives comprising essential oils, water-soluble vitamins, enzymes, proteins and zinc salts, other H-regulators, preserving agents, and/or consistency agents, where a weight ratio of the poloxamers and the alcohol is 1.3:1-1:1. An independent claim is included for spay- or spray applicator comprising 10-100 ml of the preparation.</p> |
申请公布号 |
DE102013001151(A1) |
申请公布日期 |
2014.07.24 |
申请号 |
DE20131001151 |
申请日期 |
2013.01.24 |
申请人 |
MERZ PHARMA GMBH & CO. KGAA |
发明人 |
BERLEKAMP, UWE;MÖHLE, MELANIE |
分类号 |
A61K33/14;A61K31/047;A61K31/765;A61K33/30;A61K36/00;A61K38/43;A61P11/02;A61P37/08 |
主分类号 |
A61K33/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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