Genetically modified photoautotrophic ethanol producing host cells, method for producing the host cells, constructs for the transformation of the host cells, method for testing a photoautotrophic strain for a desired growth property and method of producing ethanol using the host cells

摘要

In one embodiment the invention provides a genetically modified photoautotrophic, ethanol producing host cell comprising: - at least one first genetic modification changing the enzymatic activity or affinity of an endogenous host cell enzyme, - the first genetic modification resulting in an enhanced level of biosynthesis of acetaldehyde, pyruvate, acetyl - CoA or precursors thereof compared to the respective wild type host cell, - at least one second genetic modification different from the first genetic modification comprising an overexpressed enzyme for the formation of ethanol.