| 发明名称 |
TETRAVALENT AND MIXED HEAD BIVALENT DENGUE VACCINE |
| 摘要 |
The present invention relates to immunogenic compositions and vaccines of flavivirus. In particular, the present invention relates to improved Dengue vaccines and the design and making of such vaccines that enhance immunogenicity of the vaccine. The vaccines and immunogenic compositions of the present invention relate to mixed head bivalent flagellin-dengue antigen fusion proteins which can be combined with other bivalent dengue antigen fusion proteins or monovalent dengue antigen fusion proteins to produce multivalent vaccine including tetravalent vaccines. |
| 申请公布号 |
US2014205624(A1) |
申请公布日期 |
2014.07.24 |
| 申请号 |
US201213261724 |
申请日期 |
2012.02.28 |
| 申请人 |
Song Langzhou;Liu Ge;Tussey Lynda |
发明人 |
Song Langzhou;Liu Ge;Tussey Lynda |
| 分类号 |
A61K39/12;C07K14/005 |
主分类号 |
A61K39/12 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An immunogenic fusion protein comprising flagellin and two distinct dengue virus antigens. |
| 地址 |
Freehold NJ US |
