摘要 |
<p>Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a mimic, thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, disease, or injury in mammals, including in human beings.</p> |
申请人 |
HENRY FORD HEALTH SYSTEM |
发明人 |
LIU, XIANSHUANG;ZHANG, ZHENGGANG;CHOPP, MICHAEL;WANG, LEI;HAMILTON, DOUGLAS A.;BENNETT, JAMES W.;HALL, KEITH |