主权项 |
1. A compound of Formula (I)or a pharmaceutically acceptable salt thereof, wherein
each m is independently 0 or 1; each n is independently 0 or 1; L is a bond or is selected fromwherein each group is drawn with its left end attached to the benzimidazole and its right end attached to R1;
R1 is selected from each R2 is independently selected from alkyl and halo; each R3 is independently selected from hydrogen and —C(O)R7; R4 is alkyl; R5 and R6 are independently selected from hydrogen, alkyl, cyanoalkyl, and halo, or R5 and R6, together with the carbon atoms to which they are attached, form a six- or seven-membered ring optionally containing one heteroatom selected from nitrogen and oxygen and optionally containing an additional double bond; and each R7 is independently selected from alkoxy, alkyl, arylalkoxy, arylalkyl, cycloalkyl, (cycloalkyl)alkyl, heterocyclyl, heterocyclylalkyl, (NRcRd)alkenyl, and (NRcRd)alkyl;provided that when L is other thanand R1 is other thanthen either at least one of R5 and R6 is alkyl or cyanoalkyl, or at least one R7 is arylalkoxy or (cycloalkyl)alkyl. |