FACTOR 1 PROTEIN, FACTOR 2 PROTEIN AND INHIBITORS THEREOF FOR USE IN TREATING OR PREVENTING DISEASES

摘要

The present invention relates to proteins comprising amino acid sequences encoded by nucleic acids derived from the human chromosomal region C19Orf10 termed Factor1 and/or C19Orf63 termed Factor 2 for the use in enhancing proliferation and/or healing and/or inhibiting apoptosis of none-transformed tissue or none-transformed cell or inhibitors thereof. The invention further relates to the use of inhibitors of factor1 and factor 2 for medical use, preferably for use in treating or preventing a disease in which angiogenesis contributes to disease development or progression.