发明名称 Neuregulin based methods and compositions for treating cardiovascular disease
摘要 The present invention relates to compositions and methods for preventing, treating or delaying various cardiovascular diseases or disorders in mammals, particularly in humans. More particularly, the present invention provides for compositions and methods for preventing, treating or delaying various cardiovascular diseases or disorders using, inter alia, a neuregulin protein, or a functional fragment thereof, or a nucleic acid encoding a neuregulin protein, or a functional fragment thereof, or an agent that enhances production and/or function of said neuregulin.
申请公布号 US8785387(B2) 申请公布日期 2014.07.22
申请号 US201012879023 申请日期 2010.09.10
申请人 Zensun (Shanghai) Science & Technology Limited 发明人 Zhou Mingdong
分类号 A61K38/36 主分类号 A61K38/36
代理机构 Jones Day 代理人 Jones Day
主权项 1. A method for treating myocardial infarction or heart failure caused by myocardial infarction in a mammal, comprising administering to a mammal in need thereof a neuregulin 1 protein in an amount from about 10 U/kg to about 400 U/kg of body weight of the mammal once a day.
地址 Shanghai CN