发明名称 Compuestos derivados de tetrahidroisoquinolina sustituidos, inhibidores del factor de coagulacion xia (fxia); composicion farmaceutica que los comprende; y su uso para el tratamiento de un trastorno tromboembolico o inflamatorio seleccionado de angina inestable, sindrome coronario agudo y fibrilacion atrial, entre otros.
摘要 or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.
申请公布号 CL2014000925(A1) 申请公布日期 2014.07.18
申请号 CL20140000925 申请日期 2014.04.11
申请人 BRISTOL-MYERS SQUIBB COMPANY 发明人 ORWAT, MICHAEL J.;PINTO, DONALD J.P.;SMITH II, LEON M.;SRIVASTAVA, SHEFALI
分类号 C07D401/04;A61K31/437;A61K31/4375;A61K31/4725;A61P7/02;A61P29/00;C07D401/10;C07D401/14;C07D413/14;C07D471/10;C07D487/04;C07D487/08;C07D487/10;C07D491/10 主分类号 C07D401/04
代理机构 代理人
主权项
地址