发明名称 |
Compuestos derivados de tetrahidroisoquinolina sustituidos, inhibidores del factor de coagulacion xia (fxia); composicion farmaceutica que los comprende; y su uso para el tratamiento de un trastorno tromboembolico o inflamatorio seleccionado de angina inestable, sindrome coronario agudo y fibrilacion atrial, entre otros. |
摘要 |
or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments. |
申请公布号 |
CL2014000925(A1) |
申请公布日期 |
2014.07.18 |
申请号 |
CL20140000925 |
申请日期 |
2014.04.11 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ORWAT, MICHAEL J.;PINTO, DONALD J.P.;SMITH II, LEON M.;SRIVASTAVA, SHEFALI |
分类号 |
C07D401/04;A61K31/437;A61K31/4375;A61K31/4725;A61P7/02;A61P29/00;C07D401/10;C07D401/14;C07D413/14;C07D471/10;C07D487/04;C07D487/08;C07D487/10;C07D491/10 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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