发明名称 |
STABILIZING POLYPEPTIDES WHICH HAVE BEEN EXPOSED TO UREA |
摘要 |
Methods for stabilizing polypeptides, such as anti-HER2 antibodies, which have been exposed to urea. |
申请公布号 |
US2014199321(A1) |
申请公布日期 |
2014.07.17 |
申请号 |
US201414165098 |
申请日期 |
2014.01.27 |
申请人 |
Genentech, Inc. |
发明人 |
Emery Jefferson C.;McDonald Paul J.;O'Leary Rhona M. |
分类号 |
A61K47/18;A61K39/395 |
主分类号 |
A61K47/18 |
代理机构 |
|
代理人 |
|
主权项 |
1. An isolated composition comprising a purified anti-HER2 antibody, and urea and an amino acid added to said antibody. |
地址 |
South San Francisco CA US |