发明名称 NOVEL HETERODIMERIC PROTEINS
摘要 The invention provides novel heterodimeric proteins including heterodimeric antibodies. The present invention describes novel immunoglobulin compositions that simultaneously co-engage antigens, where both of the antigens are bound monovalently. The novel immunoglobulins described preferably utilize heterodimeric Fe regions. Methods of using the novel immunoglobulin compositions, particularly for therapeutic purposes, are also described herein.
申请公布号 CA2898100(A1) 申请公布日期 2014.07.17
申请号 CA20142898100 申请日期 2014.01.14
申请人 XENCOR, INC. 发明人 DESJARLAIS, JOHN;MOORE, GREGORY;RASHID, RUMANA;BERNETT, MATTHEW J.
分类号 C07K16/46;A61K39/395;A61P35/00;C07K16/28;C12N15/13 主分类号 C07K16/46
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