发明名称 |
DIFFERENTIAL CEREBROSPINAL FLUID REACTIVITY TO PFDN5-ALPHA FOR DETECTION OF B-CELL ACUTE LYMPHOBLASTIC CENTRAL NERVOUS SYSTEM LEUKEMIA |
摘要 |
<p>A method of managing treatment in a patient with B-cell acute lymphoblastic leukemia (B-ALL) for central nervous system (CNS) leukemia is disclosed. The method comprises obtaining cerebrospinal fluid (CSF) from the patient, obtaining a cell proteome including PFDN5-αfrom the patient, detecting reactivity of CSF against the PFDN5-α, comparing reactivity profile of CSF against the PFDN5-αat diagnosis and during treatment, and determining the status of proliferation of leukemia in the patient depending on the comparison. The method further comprises treating the patient for CNS leukemia based on the status of proliferation.</p> |
申请公布号 |
WO2014108855(A1) |
申请公布日期 |
2014.07.17 |
申请号 |
WO2014IB58167 |
申请日期 |
2014.01.10 |
申请人 |
AMRITA VISHWA VIDYAPEETHAM |
发明人 |
MENON, KRISHNA KUMAR N.;XAVIER, TESSY;HARIDASAN, ADHWYTH |
分类号 |
G01N33/574;G01N33/53;G01N33/68 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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