发明名称 |
METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS |
摘要 |
Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries. |
申请公布号 |
US2014199329(A1) |
申请公布日期 |
2014.07.17 |
申请号 |
US201214119499 |
申请日期 |
2012.05.25 |
申请人 |
Wagner Denisa D.;Fuchs Tobias A.;De Meyer Simon;Martinod Kimberly;Brill Alexander;Thomas Grace M. |
发明人 |
Wagner Denisa D.;Fuchs Tobias A.;De Meyer Simon;Martinod Kimberly;Brill Alexander;Thomas Grace M. |
分类号 |
A61K38/46;A61M1/34;A61K31/166;A61K45/06;A61K39/395 |
主分类号 |
A61K38/46 |
代理机构 |
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代理人 |
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主权项 |
1. (canceled) |
地址 |
Dover MA US |