| 发明名称 |
ADJUVANT CHEMOTHERAPY FOR ANAPLASTIC GLIOMAS |
| 摘要 |
The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may be used alone or combined with other traditional chemo- and radiotherapies and surgery, to treat or prevent glioma occurrence, recurrence, spread, growth, metastasis, or vascularization. |
| 申请公布号 |
US2014200234(A1) |
申请公布日期 |
2014.07.17 |
| 申请号 |
US201414159753 |
申请日期 |
2014.01.21 |
| 申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
TOWNER Rheal A.;FLOYD Robert A. |
| 分类号 |
A61K31/4748;A61K45/06;A61K31/166;A61K31/15;A61K31/175 |
主分类号 |
A61K31/4748 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of treating a glioma in a subject comprising administering to said subject a dose of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) effective to inhibit the vascularization, growth or spread of said glioma. |
| 地址 |
Oklahoma City OK US |
