EFFICIENTE PROCEDIMENTO PER LA PREPARAZIONE DI LAPATINIB E SUOI SALI MEDIANTE NUOVI INTERMEDI

摘要

The present invention refers to a new efficient process for the synthesis of the active pharmaceutical ingredient Lapatinib and salts thereof. In particular, the present synthesis is carried out employing new intermediates in which the amine function is protected by a group cleavable in basic milieu that provides a higher overall yield of the synthesis process.