| 摘要 |
In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| 主权项 |
1. A process for making a hydrolysis-resistant silicone compound having a sterically hindered terminal silicon group, the process comprising the step of reacting an alkoxysilyl compound having the structure: with one or more silyl halide compounds having the structure: wherein X1, X2, and X3 independently represent a halogen selected from the group consisting of chlorine, bromine, and iodine; wherein M represents a radical-polymerizable group; wherein L represents an optionally substituted divalent C1-C20 organic group; wherein n represents an integer of from 0 to 200; wherein Q1, Q2, and Q3 independently represent hydrogen or a hydrolyzable group; wherein Z1 to Z11 independently represent optionally substituted C1-C20 alkyl groups or optionally substituted C6-C20 aryl groups, with the provisos that:
at least one of Z3, Z4, and Z9 is methyl, and at least one is an organic group having at least two carbon atoms,at least one of Z5, Z6, and Z10 is methyl, and at least one is an organic group having at least two carbon atoms, andat least one of Z7, Z8, and Z11 is methyl, and at least one is an organic group having at least two carbon atoms;wherein a, a′, b, b′, c, and c′ independently represent integers of from 0 to 20; andwherein (a+a′), (b+b′), and (c+c′) are, independently, integers of from 0 to 20,with the proviso that (a+a′), (b+b′), and (c+c′) are not simultaneously 0. |
