主权项 |
1. A pharmaceutical composition comprising as an active ingredient a compound of formula (1) wherein each R1 is a non-interfering substituent independently selected from the group consisting of halo, nitro, OR2, OCOR2, COOR2, R2NCOR2, CONR22, COR2, NR22, S(O)mR2, —CN and R3, where each R2 is independently H or alkyl (1-4)
R3 is alkyl (1-6) or substituted alkyl (1-6) wherein the substituents are halo, OR2 or NR22,m is 0, 1 or 2,n is 0, 1 or 2, X is O or S, Y is NR or O, Z is CR2A2 or A,
wherein each A is independently phenyl optionally substituted by 1-3 R4 substituents wherein R4 is defined the same as R1 as above, or the pharmaceutically acceptable salts thereof. |