| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: described is a novel compound of formula I,where X and Y stand for O or S, R, R, G- Gstand for H or Calkyl; Rand Ris H or Calkyl; Ris H or phenyl; G- Gand G- Gare H; Gis trifluoromethyl, a pharmaceutical composition containing it, methods of obtaining, an initial compound in methods described and a method of obtaining the initial compound and application of the formula I compound for treatment or prevention of a disease by activation of receptor ?(PPAR?); the said disease represents metabolic syndrome, obesity, dyslipidemia, pathological glycemia, insulin resistance, senile dementia and tumours.EFFECT: obtaining the formula I compounds for treatment or prevention of the disease by activation of receptor ?(PPAR?).20 cl, 47 ex, 3 dwg, 5 tbl |
