FLT3 KINASE-INHIBITION METHOD

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for therapy of leukemia but not hairy cell leukemia where activity of FLT3 kinase is reduced or suppressed.SOLUTION: In a method for reducing or suppressing FLT3 kinase activity in a cell or subject, the following compound are used: 4-cyano-1H-imidazole-2-carboxylic acid{2-cyclohexo-1-enyl-4-[1-(2-dimethylamino-acetyl)-piperidine-4-yl]-phenyl}-amide or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The compound is used in prevention or therapy of cell proliferative diseases and/or FLT3 related diseases in a subject and also in a method for therapy of a cancer or other cell proliferative diseases.