ABUSE-PROOFED, EXTENDED RELEASE PHARMACEUTICAL COMPOSITION COMPRISING TAPENTADOL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PROCESSES FOR PREPARING THEREOF
摘要
<p>The present invention relates to an abuse-proofed, extended release pharmaceutical composition and process of preparation thereof, for oral administration comprising; Tapentadol or a pharmaceutically acceptable salt thereof; as an active ingredient; at least one Hydrogenated vegetable oil as an extended release agent; at least one polyalkylene oxide polymer and; at least one aversive agent, and nasal irritating agent and said composition having a breaking strength of less than 200N.</p>
