发明名称 |
Amphoteric liposomes comprising neutral lipids |
摘要 |
An amphoteric liposome comprising neutral lipids wherein said neutral lipids are selected from the group comprising cholesterol or mixtures of cholesterol and at least one neutral or zwitterionic lipid and wherein K (neutral) of said mixtures is 0.3 or less. Said amphoteric liposome may encapsulate an active agent, such as nucleic acid therapeutics. Also disclosed are pharmaceutical compositions comprising said amphoteric liposomes as a carrier for the delivery or targeted delivery of active agents or ingredients. |
申请公布号 |
AU2008309880(B2) |
申请公布日期 |
2014.07.10 |
申请号 |
AU20080309880 |
申请日期 |
2008.10.12 |
申请人 |
MARINA BIOTECH, INC. |
发明人 |
PANZNER, STEFFEN;SIEPI, EVGENIOS;VINZENS, UTE;MULLER, CLAUDIA;LUTZ, SILKE |
分类号 |
A61K9/127;A61K8/14;A61K31/575;A61K31/58;A61P35/00;A61P37/02;C07J41/00;C07J43/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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