NON-INVASIVE VENTILATION MEASUREMENT

摘要

Determining the lung compliance and lung resistance of a subject undergoing respiratory therapy using non-invasive ventilation requires taking the presence of leaks into account. In particular, variable and unintentional leaks at or near a subject interface appliance may be dynamically determined based on an average resistance of the leak orifice of the subject.

主权项

1. A system configured to measure respiratory parameters during application of non-invasive respiratory therapy of a subject, the system comprising:
one or more processors configured to execute computer program modules, wherein the computer program modules comprise:
a timing module configured to determine transitions in breathing between inhalations and exhalations;a passive compliance module configured to determine a passive exhalation lung compliance during an exhalation, wherein the determination by the passive compliance module is based on a passive lung model, and wherein the exhalation is demarcated based on the transitions;a passive resistance module configured to determine a passive exhalation lung resistance during the exhalation, wherein the determination by the passive resistance module is based on the passive lung model;an active compliance module configured to determine an active lung compliance that reflects an active lung model, wherein the active lung compliance is determined based on the passive exhalation lung compliance and a subject breathing mode;an active resistance module configured to determine an active lung resistance that reflects the active lung model, wherein the active lung resistance is determined based on the passive exhalation lung resistance and the subject breathing mode; anda flow module configured to determine an instantaneous estimated subject flow, wherein the flow module takes a presence of both (i) instantaneous known respiratory circuit leaks and (ii) instantaneous unknown respiratory circuit leaks into account to determine the instantaneous estimated subject flow.