| 主权项 |
1. A compound of the formula I in which R1 and R2 are independently of one another hydrogen, C1-C3-alkyl, C1-C3-fluoroalkyl, C1-C3-alkoxy, C1-C3-fluoroalkoxy, halogen or CN; R3 is hydrogen or C1-C4-alkyl; R4 is ethoxy, fluorinated ethoxy or isopropoxy; R5 is hydrogen or methyl; R6 is Br, Cl, F or CN; R7 is Cl, F or CN; R8 and R9 are independently of one another C1-C3-alkyl or C1-C3-fluoroalkyl; X1 is O, NH or CH2; X2 and X3 are N or CH, with the proviso that X2 and X3 are not simultaneously N; X4 is N or CH; a and b are independently of one another 0, 1 or 2; and m, n, o and p are independently of one another 1, 2 or 3; and their pharmaceutically acceptable salts and prodrugs thereof. |
