| 发明名称 |
FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN |
| 摘要 |
<p>This invention relates to novel fused tricyclic compounds under Formula I that are inhibitors of mammalian Target of Rapamycin (mTOR) kinase, which is also known as FRAP, RAFT, RAPT or SEP, and are useful in the treatment of cellular proliferative diseases, for example cancer and other proliferative disorders.</p> |
| 申请公布号 |
EP2608668(A4) |
申请公布日期 |
2014.07.09 |
| 申请号 |
EP20110820437 |
申请日期 |
2011.08.22 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
MENG, ZHAOYANG;REDDY, PANDURANGA ADULLA, P.;SIDDIQUI, M. ARSHAD;MANDAL, AMIT, K.;LIU, DUAN;ZHAO, LIANYUN;MCRINER, ANDREW |
| 分类号 |
C07D471/14;A61K31/4375;A61P35/00;C07D519/00 |
主分类号 |
C07D471/14 |
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