| 发明名称 | Medicament for therapeutic treatment and/or improvement of sepsis | ||
| 摘要 | A medicament for therapeutic treatment and/or improvement of sepsis in a patient with severe sepsis accompanied with one or more organ dysfunctions, wherein a value of International Normalized Ratio (INR) of a plasma specimen obtained from said patient is more than 1.4, which comprises thrombomodulin as an active ingredient. | ||
| 申请公布号 | US8772239(B2) | 申请公布日期 | 2014.07.08 |
| 申请号 | US201213676248 | 申请日期 | 2012.11.14 |
| 申请人 | Asahi Kasei Pharma Corporation | 发明人 | Tsuruta Kazuhisa;Aoki Yoshikazu;Osawa Yutaka;Kaul Inder |
| 分类号 | A61K38/36;A61K38/57;C12N15/09;A61K38/00 | 主分类号 | A61K38/36 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A method for therapeutic treatment of sepsis, which comprises the step of: administering thrombomodulin to a patient with severe sepsis, accompanied with one or more organ dysfunctions selected from the group consisting of liver dysfunction, kidney dysfunction, respiratory organ dysfunction and circulatory organ dysfunction, wherein a value of International Normalized Ratio (INR) of a plasma specimen obtained from said patient is more than 1.4. | ||
| 地址 | Tokyo JP | ||