Percutaneous absorption enhancer and transdermal preparation using the same

摘要

Provided are a percutaneous absorption enhancer excellent in an enhancing effect on percutaneous absorption of a wide range of drugs and excellent in compatibility with an adhesive base, and a transdermal preparation using the percutaneous absorption enhancer. The percutaneous absorption enhancer includes a sulfosuccinate or a salt thereof and an alkyl glycoside or an alkyl thioglycoside.

主权项

1. A matrix-type transdermal preparation, comprising:
a tape comprising drug containing layers comprising an adhesive base, a percutaneous absorption enhancer comprising 0.01 to 10% of a sulfosuccinate or a salt thereof and 0.01 to 10% of an alkyl glycoside or an alkyl thioglycoside, wherein the sulfosuccinate or a salt thereof and the alkyl glycoside or the alkyl thioglycoside are present in a total amount of from 0.1 to 20%; and a drug.