| 发明名称 |
Pharmaceutical composition containing an anti-nucleating agent |
| 摘要 |
Pharmaceutical compositions suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a drug compound in the form of a salt, wherein the drug salt is characterized by conversion to a less soluble form of the drug compound under certain pH conditions, and an anti-nucleating agent. |
| 申请公布号 |
US8771733(B2) |
申请公布日期 |
2014.07.08 |
| 申请号 |
US200511792190 |
申请日期 |
2005.12.02 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Cruanes Maria T.;Xu Wei;Artino Laura M.;Zhu Honggang |
| 分类号 |
A61K31/519;A61K9/20;A61K31/513 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
Bergman Jeffrey P.;Heber Sheldon O. |
| 主权项 |
1. A pharmaceutical composition for oral administration as a solid dose, which comprises: (a) from 2 to 15 wt. % of an anti-nucleating agent which comprises a hydroxyalkylcellulose, and (b) from 5 to 75 wt. % of a potassium salt of Compound A, wherein Compound A is: |
| 地址 |
Rahway NJ US |
