发明名称 |
Pharmaceutical Composition for Preventing or Treating Aging-related Diseases Comprising Blocker of Progerin and Lamin A Binding and Screening Method Thereof |
摘要 |
PURPOSE: A pharmaceutical composition for preventing or treating aging-related diseases and a method for screening a binding inhibitor are provided to effectively treat or prevent diseases caused by progerin and to specifically select a drug which suppresses binding between progerin and lamin A. CONSTITUTION: A compound of chemical formula 1 or 2 or a pharmaceutically acceptable salt thereof is provided. A pharmaceutical composition for preventing or treating aging-related diseases contains the compound of chemical formula 1 or 2 or a pharmaceutically acceptable salt thereof as an active ingredient. A method for screening a therapeutic agent for treating aging-related diseases comprises the step of selecting candidate drugs which suppress binding between progerin and lamin A. |
申请公布号 |
KR101407044(B1) |
申请公布日期 |
2014.07.04 |
申请号 |
KR20120027028 |
申请日期 |
2012.03.16 |
申请人 |
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发明人 |
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分类号 |
A61K31/352;A61P35/00;C07D311/06;C07D493/04 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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