| 发明名称 |
PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RESPONSIVE TO PROTEASOME INHIBITION |
| 摘要 |
The invention disclosed herein generally relates to methods and compositions for inhibiting proteasome activity comprising a syrbactin compound having the structure of Formula I or II:; |
| 申请公布号 |
US2014187526(A1) |
申请公布日期 |
2014.07.03 |
| 申请号 |
US201314094581 |
申请日期 |
2013.12.02 |
| 申请人 |
Pono Corporation |
发明人 |
Bachmann Andre S.;Dudler Robert;Groll Michael |
| 分类号 |
C07D245/02 |
主分类号 |
C07D245/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for inhibiting proteasome activity in a cell comprising:
contacting a cell with an amount of a compound of the formula: effective to inhibit proteasome activity of said cell; andconfirming inhibition of proteasome activity. |
| 地址 |
Honolulu HI US |
