发明名称 |
TARGETED CONJUGATES ENCAPSULATED IN PARTICLES AND FORMULATIONS THEREOF |
摘要 |
Particles, including nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are provided. Methods of administering the formulations to a subject in need thereof are provided, for example, to treat or prevent cancer or infectious diseases. |
申请公布号 |
WO2014106208(A1) |
申请公布日期 |
2014.07.03 |
申请号 |
WO2013US78361 |
申请日期 |
2013.12.30 |
申请人 |
BLEND THERAPEUTICS, INC. |
发明人 |
BILODEAU, MARK, T.;KADIYALA, SUDHAKAR;SHINDE, RAJESH;WHITE, BRIAN;WOOSTER, RICHARD;BARDER, TIMOTHY, EDWARD |
分类号 |
A61K47/48;A61K9/51;B82Y5/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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地址 |
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