发明名称 DIPHENYL SULFIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT WHICH CONTAINS SAME AS ACTIVE INGREDIENT
摘要 [Problem] To provide a diphenyl sulfide derivative which is useful as a pharmaceutical product that has excellent S1P3 antagonist activity. [Solution] The inventors have discovered that a diphenyl sulfide derivative represented by general formula (1) (wherein R1 represents an alkoxy group having 1-6 carbon atoms, R2 represents a propyl group or an allyl group, X represents methylene or an oxygen atom, and Z represents a halogen atom) has excellent S1P3 antagonist activity as a result of extensive researches for the production of a compound that has S1P3 antagonist activity.
申请公布号 EP2657241(A4) 申请公布日期 2014.07.02
申请号 EP20110850843 申请日期 2011.12.20
申请人 KYORIN PHARMACEUTICAL CO., LTD. 发明人 ISHIKAWA, KUMI;KOGA, SHIGERU;KOHNO, YASUSHI;FUJII, KIYOSHI;YOSHIKAWA, KEN
分类号 C07F9/09;A61K31/661;A61K31/662;A61P7/02;A61P9/00;A61P9/06;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/16;A61P35/00;A61P43/00;C07F9/38 主分类号 C07F9/09
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