发明名称 |
DEVELOPMENT AND USE OF FLUORESCENT PROBES OF UNBOUND BILIRUBIN |
摘要 |
Identification and use of proteins fluorescently labeled and that undergo a change in fluorescence index upon binding bilirubin are described. Probes are disclosed which are labeled at a cysteine or lysine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for determination of unbound bilirubin levels in a fluid sample. |
申请公布号 |
EP2748615(A2) |
申请公布日期 |
2014.07.02 |
申请号 |
EP20120827317 |
申请日期 |
2012.08.24 |
申请人 |
KLEINFELD, ALAN M. |
发明人 |
HUBER, ANDREW, HENRY;KAMPF, JAMES, PATRICK;KWAN, THOMAS;ZHU, BAOLONG |
分类号 |
G01N33/72;C07K14/47;G01N33/533;G01N33/68;G06F17/10 |
主分类号 |
G01N33/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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