| 摘要 |
The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides. |
| 主权项 |
1. A method for treatment of dandruff, comprising topical application to a person in need of treatment of dandruff of a composition comprising a cosmetic carrier and a Malassezia furfur-inhibiting amount of at least one peptide with a sequence or a repetitive sequence motif according to SEQ ID NO: 2:(SEQ ID NO: 2)X1 X2K X3 X4 X5KIP X11 X12 KFX6X7 X8 AX9KF in which X1 is lysine, arginine or phenylalanine, X2 is lysine or tryptophan, X3 is leucine or lysine, X4 is phenylalanine or leucine, X5 is leucine or lysine, X6 is leucine or lysine, X7 is histidine or lysine, X8 is alanine, leucine, valine or serine, X9 is leucine or lysine, X11 is proline or a chemical bond, and X12 is proline or a chemical bond, where the repetitive sequence motifs are identical or different; or peptide derivatives thereof selected from the group consisting of aliphatic esters, amides, N-acyl peptides, O-acyl peptides, and peptides wherein between 1 to 5 arbitrary amino acid residues are N- and/or C-terminally added or deleted. |
